Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CALML3 | P27482 | 1/20 | 0.43 |
| ▸ | SDHA | P31040 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481286 | 1.00 | MAOA (0.47) | MAOAUSP30KMOMAOBLMNA | |
| SCHEMBL5571718 | 0.89 | MAOA (0.41) | MAOAMAOBCALML3GRM2HTR6 | |
| SCHEMBL12477511 | 0.84 | MAOB (0.62) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL27629080 | 0.84 | MAOB (0.62) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL12477860 | 0.84 | MAOB (0.62) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL27482757 | 0.83 | MAOB (0.44) | MAOAUSP30KMOMAOBLMNA | |
| SCHEMBL8501013 | 0.82 | FADS1 (0.53) | MAOAMAOBLMNACALML3GRM2 | |
| SCHEMBL28109897 | 0.81 | PIK3C3 (0.38) | MAOAUSP30MAOBLMNAPTGS1 | |
| SCHEMBL8436019 | 0.81 | GRM2 (0.46) | MAOAMAOBGRM2 | |
| SCHEMBL28109789 | 0.81 | MAOB (0.51) | MAOAMAOBLMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104364240-B | A medicine for preventing or treating mycobacterial diseases | 四川贝力克生物技术有限责任公司 | 2017-02-22 | — | — | CN | disclosed |