Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29624374 | 0.84 | HPGD (0.55) | ALDH1A1KDM4EHSD17B10TDP1KMT2A | |
| SCHEMBL583659 | 0.84 | HPGD (0.55) | ALDH1A1KDM4EHSD17B10TDP1KMT2A | |
| SCHEMBL2799632 | 0.73 | PRKDC (0.42) | ALDH1A1KDM4EKMT2AMEN1IGF1R | |
| SCHEMBL30286495 | 0.73 | PRKDC (0.42) | ALDH1A1KDM4EKMT2AMEN1IGF1R | |
| SCHEMBL9860604 | 0.72 | LMNA (0.54) | ALDH1A1KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL14070022 | 0.71 | LMNA (0.64) | ALDH1A1HSD17B10TDP1KMT2AMEN1 | |
| SCHEMBL15152237 | 0.71 | SMN1; SMN2 (0.51) | ALDH1A1KMT2AMEN1IGF1RMAPT | |
| SCHEMBL15152345 | 0.71 | PRKDC (0.40) | ALDH1A1KDM4EHSD17B10TDP1KMT2A | |
| SCHEMBL29447932 | 0.70 | HPGD (0.55) | ALDH1A1HSD17B10TDP1KMT2AMEN1 | |
| SCHEMBL1464773 | 0.70 | HPGD (0.55) | ALDH1A1HSD17B10TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104144930-B | New indolizine derivatives, method for preparing same and pharmaceutical compositions containing same | 瑟维尔实验室 | 2017-02-22 | — | — | CN | disclosed |