Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28353515 | 0.82 | ADORA2A (0.55) | ADORA2ANPC1RAB9AATMADORA1 | |
| SCHEMBL2319415 | 0.77 | BACE1 (0.58) | ADORA2ARAB9ABACE1ADORA1ADORA3 | |
| SCHEMBL29726798 | 0.75 | MEN1 (0.57) | ADORA2ANPC1RAB9AATMADORA1 | |
| SCHEMBL16305319 | 0.75 | MEN1 (0.57) | ADORA2ANPC1RAB9AATMADORA1 | |
| SCHEMBL4264929 | 0.75 | BACE1 (0.51) | ADORA2ABACE1ADORA1ADORA3KDM4E | |
| SCHEMBL17803694 | 0.73 | PDE5A (0.60) | ADORA2ANPC1RAB9AATMADORA1 | |
| SCHEMBL27554413 | 0.73 | KDM4E (0.51) | ADORA2ABACE1ADORA1ADORA3ADORA2B | |
| SCHEMBL13408684 | 0.73 | NPC1 (0.49) | ADORA2ANPC1RAB9AATMADORA1 | |
| SCHEMBL28009753 | 0.73 | ADORA2A (0.57) | ADORA2ANPC1RAB9AADORA1ADORA3 | |
| SCHEMBL8087934 | 0.72 | TGFBR1 (0.65) | ADORA2ANPC1RAB9AATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106167502-A | Azetepa compound and preparation method thereof and the application as insecticide thereof | 广西师范学院 | 2016-11-30 | — | — | CN | disclosed |
| CN-106117268-A | α aminophosphonate compound with 2 amino 1,3,4 thiadiazoles structures and preparation method thereof and purposes | 广西师范学院 | 2016-11-16 | — | — | CN | disclosed |