Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PDE5A | O76074 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13130593 | 0.83 | ACHE (0.56) | ADORA2AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29658035 | 0.83 | ACHE (0.56) | ADORA2AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6299090 | 0.78 | ACHE (0.49) | ADORA2AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22899959 | 0.78 | ACHE (0.53) | ADORA2AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16314329 | 0.75 | KDM4E (0.49) | ADORA2AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13978921 | 0.75 | ACHE (0.50) | ADORA2AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4857297 | 0.75 | RPS6KB2 (0.55) | ADORA2AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29361026 | 0.75 | RPS6KB2 (0.55) | ADORA2AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1502392 | 0.75 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL28413818 | 0.73 | ACHE (0.49) | ADORA2AKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104557856-A | Preparation method for 9,9-diaryl thiophene xanthene-10,10-dioxide | UNIV NANJING POSTS & TELECOMM | 2015-04-29 | — | — | CN | disclosed |