Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5479824 | 0.75 | DDB1 (0.40) | DDB1CRBN | |
| SCHEMBL739596 | 0.74 | PSEN1 (0.41) | DDB1CRBNDPP4DPP8DPP9 | |
| SCHEMBL29157521 | 0.72 | DDB1 (0.55) | DDB1CRBNDPP4DPP8DPP9 | |
| SCHEMBL1717738 | 0.69 | DDB1 (0.39) | DDB1CRBN | |
| SCHEMBL4630809 | 0.68 | DRD2 (0.33) | — | |
| SCHEMBL6229055 | 0.67 | GAA (0.41) | DDB1CRBN | |
| SCHEMBL1240861 | 0.67 | EPHX2 (0.39) | — | |
| SCHEMBL9408684 | 0.66 | GAA (0.32) | — | |
| SCHEMBL1242072 | 0.66 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL20355507 | 0.66 | JAK3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106257976-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2016-12-28 | — | — | CN | disclosed |