SCHEMBL28111124

SCHEMBL28111124

COCc1ccc(COC=O)cc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.41
PTGS2 P35354 1/20 0.38
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
ACACB O00763 1/20 0.35
AGXT P21549 4/20 0.34
IDO1 P14902 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
CA2 P00918 3/20 0.33
SRC P12931 1/20 0.33
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33
CA9 Q16790 2/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11392894 0.88 CA2 (0.39) AGXTIDO1CA2SRCCA9
SCHEMBL6342 0.83 IDO1 (0.55) TP53AGXTIDO1NPC1RAB9A
SCHEMBL146541 0.82 AGXT (0.52) LMNAAGXTIDO1NPC1RAB9A
SCHEMBL147464 0.82 ALDH1A1 (0.43) LMNATP53NPC1RAB9ATDP1
SCHEMBL11316154 0.81 ESR1 (0.42) TP53NPC1RAB9ATDP1CA2
SCHEMBL11320245 0.81 IDO1 (0.41) ERN1LMNAAGXTIDO1NPC1
Iodide SCHEMBL9356671 0.81 IDO1 (0.53) TP53AGXTIDO1NPC1RAB9A
SCHEMBL28552476 0.81 IDO1 (0.53) TP53AGXTIDO1NPC1RAB9A
SCHEMBL28560899 0.81 IDO1 (0.53) TP53AGXTIDO1NPC1RAB9A
SCHEMBL134443 0.80 IDO1 (0.46) ERN1PTGS2LMNATP53ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106238984-A A kind of horizontal slide rail formula self-regulated pose bonding machine and control method thereof 徐州工程学院 2016-12-21 CN claimed
CN-106238984-A A kind of horizontal slide rail formula self-regulated pose bonding machine and control method thereof 徐州工程学院 2016-12-21 CN disclosed