Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3896 | 0.85 | ALDH1A1 (0.59) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| Hydrochloric Acid SCHEMBL28253846 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| Water SCHEMBL316720 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| Ammonia Solution, Strong SCHEMBL27831351 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| SCHEMBL671499 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| SCHEMBL11039497 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| Pyrimidine SCHEMBL29199390 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| Purine SCHEMBL5315439 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4ECDK2RXFP1PAK1 | |
| Purine SCHEMBL4404745 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KDM4EFKBP5CDK2RXFP1 | |
| Purine SCHEMBL27989516 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4EFKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111529684-A | Use of oral sustained release compositions containing cyclosporin | 卓越治疗有限公司 | 2020-08-14 | — | — | CN | claimed |
| CN-114605248-A | TNF-alpha small molecule inhibitor and preparation method and application thereof | 复旦大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-114106298-A | Ferulic acid based lignin micro-nano particles capable of treating colitis and preparation method thereof | 哈尔滨工业大学（深圳） | 2022-03-01 | — | — | CN | disclosed |
| CN-113876828-A | A Chinese medicinal composition for treating digestive tract diseases, and its preparation method | 何松兴 | 2022-01-04 | — | — | CN | disclosed |
| CN-111281866-B | Traditional Chinese medicine chemical preparation for preventing or treating ulcerative colitis | 中国药科大学 | 2021-09-28 | — | — | CN | disclosed |
| CN-112341399-A | 1,2, 4-triazole derivative compounds and application thereof in treating inflammatory bowel diseases | 王健 | 2021-02-09 | — | — | CN | disclosed |
| CN-111741957-A | Heterocyclic amides as kinase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-10-02 | — | — | CN | disclosed |
| CN-106687110-B | Purified therapeutic nanoparticles and method of making same | 石药集团中奇制药技术（石家庄）有限公司 | 2020-09-18 | — | — | CN | disclosed |
| CN-111529684-A | Use of oral sustained release compositions containing cyclosporin | 卓越治疗有限公司 | 2020-08-14 | — | — | CN | disclosed |
| CN-111281866-A | Traditional Chinese medicine chemical preparation for preventing or treating ulcerative colitis | 中国药科大学 | 2020-06-16 | — | — | CN | disclosed |
| CN-107847330-B | Multi-element biological absorbable intravascular stent | 埃夫莫拉尔医疗有限责任公司 | 2020-04-03 | — | — | CN | disclosed |
| CN-106132400-A | Composition for treating ulcerative colitis | 希格默伊德药业有限公司 | 2016-11-16 | — | — | CN | disclosed |