Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 2/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | G6PD | P11413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Purine SCHEMBL27989516 | 0.98 | ALDH1A1 (0.43) | ALDH1A1FKBP5KDM4EMETAP2METAP1 | |
| Purine SCHEMBL12003983 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KDM4EMETAP2METAP1PI4KA | |
| Purine SCHEMBL6421380 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EMETAP2METAP1PI4KA | |
| Purine SCHEMBL29365913 | 0.85 | — | — | |
| Purine SCHEMBL30862524 | 0.85 | — | — | |
| Purine SCHEMBL2120554 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EMETAP2METAP1PI4KA | |
| Purine SCHEMBL3158 | 0.85 | — | — | |
| Purine SCHEMBL29703771 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EMETAP2METAP1PI4KA | |
| Purine SCHEMBL20520354 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KDM4EMETAP2METAP1PI4KA | |
| Purine SCHEMBL712798 | 0.83 | ALDH1A1 (0.45) | ALDH1A1KDM4EMETAP2METAP1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117844810-A | Promoter for improving expression level of glycinamide nucleotide synthetase and application thereof | 华南理工大学 | 2024-04-09 | — | — | CN | disclosed |
| US-7635572-B2 | Methods for conducting assays for enzyme activity on protein microarrays | Life Technologies Corporation (US) | 2009-12-22 | — | — | US | disclosed |
| EP-1642109-A4 | METHODS FOR CONDUCTING ASSAYS FOR ENZYME ACTIVITY ON PROTEIN MICROARRAYS | PROTOMETRIX INC (US) | 2007-09-05 | — | — | EP | disclosed |
| EP-1642109-A2 | METHODS FOR CONDUCTING ASSAYS FOR ENZYME ACTIVITY ON PROTEIN MICROARRAYS | Protometrix, Inc. (US) | 2006-04-05 | — | — | EP | disclosed |
| US-20050118665-A1 | Methods for conducting assays for enzyme activity on protein microarrays | PROTOMETRIX, INC. | 2005-06-02 | — | — | US | disclosed |
| WO-2005003721-A2 | ENZYME ACTIVITY ASSAYS ON PROTEIN MICROARRAYS | PROTOMETRIX, INC. (US) | 2005-01-13 | — | — | WO | disclosed |
| US-5656742-A | Ring-opened purine compounds for labeling polynucleotides | UNIVERSITY OF MIAMI (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0625985-B1 | METHOD AND RING-OPENED PURINE COMPOUNDS FOR LABELING POLYNUCLEOTIDES | UNIV MIAMI (US) | 1997-06-11 | — | — | EP | disclosed |
| US-5593829-A | Method for labeling DNA by ring-opening of purine bases | UNIVERSITY OF MIAMI (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0625985-A1 | METHOD AND RING-OPENED PURINE COMPOUNDS FOR LABELING POLYNUCLEOTIDES. | UNIV MIAMI (US) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993011146-A1 | METHOD AND RING-OPENED PURINE COMPOUNDS FOR LABELING POLYNUCLEOTIDES | UNIVERSITY OF MIAMI (US) | 1993-06-10 | — | — | WO | disclosed |