Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 7/20 | 0.39 |
| ▸ | NPY1R | P25929 | 5/20 | 0.39 |
| ▸ | NPY2R | P49146 | 4/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5606092 | 0.91 | TDP1 (0.43) | NPY4RNPY1RNPY2RNPY5RTSHR | |
| SCHEMBL2246952 | 0.87 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RDPP8 | |
| SCHEMBL28911603 | 0.86 | NPY4R (0.38) | NPY4RNPY1RNPY2RNPY5RDPP8 | |
| SCHEMBL27908189 | 0.83 | NR4A2 (0.46) | ALDH1A1HTTL3MBTL1 | |
| SCHEMBL288133 | 0.82 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL28712062 | 0.82 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL9237239 | 0.82 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL17164666 | 0.81 | NAAA (0.41) | NPY4RNPY1RNPY2RNPY5RDPP8 | |
| SCHEMBL22633923 | 0.81 | NAAA (0.41) | NPY4RNPY1RNPY2RNPY5RDPP8 | |
| SCHEMBL1401439 | 0.81 | ANPEP (0.47) | NPY4RNPY1RNPY2RNPY5RDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106139156-A | A kind of pharmaceutical composition containing quinoline or its salt | 江苏恒瑞医药股份有限公司 | 2016-11-23 | — | — | CN | disclosed |