SCHEMBL5606092

SCHEMBL5606092

N=C(N)NCCC[C@H](N)C(=O)OC(=O)c1ccccc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.43
ALOX5 P09917 3/20 0.40
LMNA P02545 2/20 0.39
TSHR P16473 2/20 0.39
NPY4R P50391 5/20 0.39
NPY1R P25929 3/20 0.39
ALDH1A1 P00352 2/20 0.38
NAAA Q02083 1/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HSD17B10 Q99714 1/20 0.38
NLRP1 Q9C000 1/20 0.38
HDAC7 Q8WUI4 1/20 0.37
NPY2R P49146 2/20 0.37
NPY5R Q15761 2/20 0.37
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28111283 0.91 NPY4R (0.39) TDP1TSHRNPY4RNPY1RALDH1A1
SCHEMBL28962981 0.90 TDP1 (0.44) TDP1ALOX5LMNATSHRALDH1A1
SCHEMBL2246952 0.84 NPY4R (0.39) TDP1NPY4RNPY1RALDH1A1MAPT
SCHEMBL28911603 0.83 NPY4R (0.38) TDP1NPY4RNPY1RALDH1A1MAPT
Arginine SCHEMBL4208935 0.81 ALDH1A1 (0.45) TDP1ALOX5TSHRNPY4RNPY1R
Arginine SCHEMBL5606089 0.81 ALDH1A1 (0.45) TDP1ALOX5TSHRNPY4RNPY1R
SCHEMBL27908189 0.80 NR4A2 (0.46) LMNAALDH1A1NPC1MAPTHPGD
SCHEMBL7790573 0.80 LMNA (0.60) TDP1LMNATSHRALDH1A1NAAA
SCHEMBL19614688 0.80 TDP1 (0.49) TDP1ALOX5LMNATSHRALDH1A1
SCHEMBL1650196 0.80 TDP1 (0.49) TDP1ALOX5LMNATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115607556-A Medicine for preventing and treating asthma, chronic obstructive pulmonary disease, allergic diseases, etc 刘力 2023-01-17 CN claimed
WO-2012177433-A1 TOPICAL COMPOSITIONS FOR THE TREATMENT OF DERMATOLOGICAL DISORDERS EVOLOGIE LLC (US) 2012-12-27 WO claimed
US-20070042009-A1 Topical composition for delivery of salicylates ALPHARX INC (CA) 2007-02-22 US claimed
EP-0936899-A4 COSMETIC COMPOSITIONS PROCTER & GAMBLE (US) 2002-01-02 EP claimed
US-6267978-B1 COSMETIC FOR REGULATION OF THE OILY AND/OR SHINY APPEARANCE OF SKIN THE PROCTER & GAMBLE COMPANY 2001-07-31 US claimed
US-6143310-A WATER IN OIL EMULSION CONTAINING AMINO ACID SALT OF SALICYLIC ACID THE PROCTER & GAMBLE COMPANY (US) 2000-11-07 US claimed
EP-0936899-A1 COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-08-25 EP claimed
CN-1226820-A Cosmetic composition PROCTER & GAMBLE (US) 1999-08-25 CN claimed
WO-1998010741-A1 COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-03-19 WO claimed
US-12409121-B2 Formulations and methods for preparing stable cosmetic compositions Spinart, LLC (US) 2025-09-09 US disclosed
US-20250049674-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE L'OREAL (FR) 2025-02-13 US disclosed
US-20250025393-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND DIPROPYLENE GLYCOL L'OREAL (FR) 2025-01-23 US disclosed
US-20250009625-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AT LEAST ONE DIOL COMPRISING FROM 4 TO 7 CARBON ATOMS L'OREAL (FR) 2025-01-09 US disclosed
US-20240423888-A1 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST ONE MEROCYANINE AND AT LEAST ASCORBIC ACID AND/OR A DERIVATIVE THEREOF L'OREAL (FR) 2024-12-26 US disclosed
EP-0936899-A4 COSMETIC COMPOSITIONS PROCTER & GAMBLE (US) 2002-01-02 EP disclosed
US-6267978-B1 COSMETIC FOR REGULATION OF THE OILY AND/OR SHINY APPEARANCE OF SKIN THE PROCTER & GAMBLE COMPANY 2001-07-31 US disclosed
US-6143310-A WATER IN OIL EMULSION CONTAINING AMINO ACID SALT OF SALICYLIC ACID THE PROCTER & GAMBLE COMPANY (US) 2000-11-07 US disclosed
EP-0936899-A1 COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-08-25 EP disclosed
CN-1226820-A Cosmetic composition PROCTER & GAMBLE (US) 1999-08-25 CN disclosed
WO-1998010741-A1 COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-03-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250009625-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AT LEAST ONE DIOL COMPRISING FROM 4 TO 7 CARBON ATOMS KRT18, DSC1, ECH1 TDP1 4657/4885ALOX5 2027/4885LMNA 665/4885
US-20240423888-A1 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST ONE MEROCYANINE AND AT LEAST ASCORBIC ACID AND/OR A DERIVATIVE THEREOF KRT18, PROC, DSC1 TDP1 4563/4885ALOX5 1275/4885LMNA 494/4885
US-20250049674-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE NAPRT, NAMPT, NNMT TDP1 669/4885ALOX5 1821/4885LMNA 1691/4885
US-20250025393-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND DIPROPYLENE GLYCOL KRT18, DSC1, DSG1 TDP1 4339/4885ALOX5 1879/4885LMNA 769/4885
US-12409121-B2 Formulations and methods for preparing stable cosmetic compositions CUTA, ARG1, ODC1 TDP1 1177/4885ALOX5 477/4885LMNA 1375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.