Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065720 | 0.87 | HRH3 (0.53) | KMT2ACA12CA9CA2HRH3 | |
| SCHEMBL28111780 | 0.84 | ACLY (0.56) | CA12CA9CA2HRH3ACLY | |
| SCHEMBL3558164 | 0.81 | CA12 (0.78) | KMT2ACA12CA9CA2L3MBTL1 | |
| SCHEMBL28111778 | 0.79 | PPARG (0.46) | HRH3ACLYPTGS2 | |
| SCHEMBL28017014 | 0.79 | CA12 (0.69) | KMT2ACA12CA9CA2L3MBTL1 | |
| SCHEMBL14583988 | 0.78 | CYP19A1 (0.56) | KMT2ACA12CA9CA2HRH3 | |
| SCHEMBL4073243 | 0.77 | HRH3 (0.52) | CA12CA9CA2HRH3L3MBTL1 | |
| SCHEMBL4073241 | 0.76 | HRH3 (0.48) | KMT2ACA12CA9CA2HRH3 | |
| SCHEMBL4073246 | 0.76 | HRH3 (0.51) | KMT2ACA12CA9CA2HRH3 | |
| SCHEMBL6295031 | 0.76 | HRH3 (0.64) | KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112358432-B | Synthetic method of indole derivatives | 天津大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-112358432-A | Synthetic method of indole derivatives | 天津大学 | 2021-02-12 | — | — | CN | disclosed |
| CN-106179294-A | A kind of method that hydrotalcite catalyst economic benefits and social benefits catalyze and synthesize benzazolyl compounds | 山东师范大学 | 2016-12-07 | — | — | CN | disclosed |