Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.69 |
| ▸ | CA9 | Q16790 | 3/20 | 0.69 |
| ▸ | CA2 | P00918 | 2/20 | 0.69 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.55 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.55 |
| ▸ | ACLY | P53396 | 3/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28414154 | 0.96 | CA12 (0.71) | CA12CA9CA2NOD1NOD2 | |
| SCHEMBL28529811 | 0.90 | CA2 (0.56) | CA12CA9CA2NOD1NOD2 | |
| SCHEMBL28017010 | 0.90 | ACLY (0.61) | CA12CA9CA2NOD1NOD2 | |
| SCHEMBL3558164 | 0.90 | CA12 (0.78) | CA12CA9CA2NOD1ACLY | |
| SCHEMBL28017016 | 0.89 | CA12 (0.63) | CA12CA9CA2NOD1NOD2 | |
| SCHEMBL28017013 | 0.89 | CA12 (0.63) | CA12CA9CA2NOD1NOD2 | |
| SCHEMBL28532284 | 0.88 | CA9 (0.61) | CA12CA9CA2NOD1NOD2 | |
| SCHEMBL29596783 | 0.87 | CA12 (0.54) | CA12CA9CA2NOD1NOD2 | |
| SCHEMBL28519189 | 0.87 | CA12 (0.54) | CA12CA9CA2NOD1NOD2 | |
| SCHEMBL28523374 | 0.87 | CA12 (0.60) | CA12CA9CA2NOD1NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592086-A | Method for preparing indole compound through copper salt catalysis | UNIV TAIZHOU | 2015-05-06 | — | — | CN | claimed |
| CN-111285792-B | 2-substituted indole compound and preparation method thereof | 三峡大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-110938027-B | Synthetic method of indole derivatives | 河北凯诺中星科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-112358432-B | Synthetic method of indole derivatives | 天津大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-109651228-B | Catalytic synthesis method of N-p-toluenesulfonyl-2-substituted indole compound | 浙江万里学院 | 2022-05-17 | — | — | CN | disclosed |
| CN-111285792-A | 2-substituted indole compound and preparation method thereof | 三峡大学 | 2020-06-16 | — | — | CN | disclosed |
| CN-104592086-B | A kind of method that Benzazole compounds are prepared by mantoquita catalysis | 台州学院 | 2017-06-06 | — | — | CN | disclosed |
| CN-104592086-A | Method for preparing indole compound through copper salt catalysis | UNIV TAIZHOU | 2015-05-06 | — | — | CN | disclosed |