Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | CTSC | P53634 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763089 | 0.78 | ESR2 (0.42) | ALDH1A1MEN1KMT2ACYP2C9SLC6A3 | |
| SCHEMBL4625352 | 0.76 | SMN1; SMN2 (0.63) | LMNAKDM4EHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9218374 | 0.75 | LMNA (0.58) | LMNAKDM4EHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL21635531 | 0.74 | LMNA (0.56) | LMNAKDM4EHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL16776722 | 0.74 | LMNA (0.56) | LMNAKDM4EHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL23521122 | 0.73 | CA2 (0.52) | KDM4ESMN1; SMN2CA12CA1CA2 | |
| SCHEMBL9506665 | 0.73 | LMNA (0.59) | LMNAKDM4EHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL5742854 | 0.73 | HPGD (0.70) | LMNAKDM4EHPGDSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6420499 | 0.73 | LMNA (0.55) | LMNAKDM4EHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL6014610 | 0.73 | HPGD (1.00) | LMNAKDM4EHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045993-A | Salt and crystal form of compound | 诺华股份有限公司 | 2016-10-26 | — | — | CN | disclosed |