Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909845 | 0.78 | HSD17B10 (1.00) | HSD17B10GABRA5GABRB2LMNAALDH1A1 | |
| SCHEMBL9864403 | 0.76 | HSD17B10 (0.96) | HSD17B10GABRA5GABRB2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9694699 | 0.76 | GABRA5 (0.96) | HSD17B10GABRA5GABRB2LMNAALDH1A1 | |
| Methyl Alcohol SCHEMBL10946415 | 0.75 | HSD17B10 (0.93) | HSD17B10GABRA5GABRB2LMNAALDH1A1 | |
| Acetic Acid SCHEMBL27742442 | 0.74 | HSD17B10 (0.89) | HSD17B10GABRA5GABRB2LMNAALDH1A1 | |
| SCHEMBL7192491 | 0.73 | HSD17B10 (0.46) | HSD17B10GABRA5GABRB2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL28729982 | 0.73 | HSD17B10 (0.60) | HSD17B10GABRA5GABRB2LMNAALDH1A1 | |
| SCHEMBL11130654 | 0.72 | HSD17B10 (0.62) | HSD17B10GABRA5GABRB2LMNAALDH1A1 | |
| SCHEMBL28111505 | 0.70 | GABRA5 (0.60) | HSD17B10GABRA5GABRB2LMNAALDH1A1 | |
| SCHEMBL8112798 | 0.70 | HSD17B10 (0.42) | HSD17B10GABRA5GABRB2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045937-A | Synthesizing method of {2-[2-(2-amino-4-thiazolyl)-amino acetyl]-4-thiazolyl}-acetic acid | 杭州诺维和医药技术有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-106045937-A | Synthesizing method of {2-[2-(2-amino-4-thiazolyl)-amino acetyl]-4-thiazolyl}-acetic acid | 杭州诺维和医药技术有限公司 | 2016-10-26 | — | — | CN | disclosed |