Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 12/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111098 | 0.87 | ACACB (0.36) | ACACBKLKB1 | |
| SCHEMBL28111162 | 0.86 | ACACB (0.37) | ACACBKLKB1ACACA | |
| SCHEMBL17064477 | 0.84 | KLKB1 (0.40) | KLKB1DPP4 | |
| SCHEMBL28529921 | 0.75 | PSEN1 (0.35) | DPP4 | |
| SCHEMBL28234892 | 0.74 | DPP4 (0.34) | ACACBKLKB1DPP4DPP9DPP7 | |
| Ammonia Solution, Strong SCHEMBL28234890 | 0.71 | DPP4 (0.34) | DPP4DPP9DPP7 | |
| SCHEMBL24222041 | 0.71 | OPRL1 (0.43) | DPP4DPP9DPP7 | |
| SCHEMBL17064969 | 0.71 | KLKB1 (0.39) | KLKB1 | |
| SCHEMBL17064820 | 0.70 | KLKB1 (0.38) | KLKB1 | |
| SCHEMBL17073498 | 0.69 | KLKB1 (0.38) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106257976-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2016-12-28 | — | — | CN | disclosed |