Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 9/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111098 | 0.87 | ACACB (0.36) | ACACBKLKB1 | |
| SCHEMBL28111673 | 0.86 | ACACB (0.35) | ACACBACACAKLKB1 | |
| SCHEMBL17064820 | 0.84 | KLKB1 (0.38) | KLKB1USP30CHRM3 | |
| SCHEMBL17073514 | 0.79 | RAB9A (0.40) | KLKB1USP30 | |
| SCHEMBL28534226 | 0.75 | CYP4F2 (0.35) | ACACBCHRM3 | |
| SCHEMBL27074546 | 0.72 | KLKB1 (0.53) | KLKB1CHRM3 | |
| SCHEMBL25805122 | 0.71 | — | — | |
| SCHEMBL17064969 | 0.71 | KLKB1 (0.39) | KLKB1CHRM3 | |
| SCHEMBL17064477 | 0.70 | KLKB1 (0.40) | KLKB1USP30CHRM3 | |
| SCHEMBL20584575 | 0.69 | KLKB1 (0.51) | KLKB1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106257976-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2016-12-28 | — | — | CN | disclosed |