Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 15/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22647296 | 0.74 | SYK (0.37) | SYK | |
| SCHEMBL29828520 | 0.74 | SYK (0.37) | SYK | |
| SCHEMBL1189830 | 0.71 | TDP1 (0.44) | GABRA1GABRB1LMNA | |
| SCHEMBL29404221 | 0.71 | TDP1 (0.44) | GABRA1GABRB1LMNA | |
| SCHEMBL15687628 | 0.68 | TDP1 (0.41) | GABRA1GABRB1LMNA | |
| SCHEMBL27823875 | 0.67 | JUN (0.33) | LMNA | |
| SCHEMBL28111753 | 0.67 | GABRA1 (0.35) | GABRA1GABRB1GLRA1CNR2LMNA | |
| SCHEMBL2153503 | 0.66 | GLRA1 (0.50) | GABRA1GABRB1GLRA1LMNAFABP3 | |
| SCHEMBL4649720 | 0.66 | CNR2 (0.37) | GABRA1GABRB1CNR2 | |
| SCHEMBL4649771 | 0.66 | GABRA1 (0.40) | GABRA1GABRB1CNR2LMNAFABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187910-A | Pyridazine class derivant and its production and use | 浙江大学 | 2016-12-07 | — | — | CN | disclosed |