Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | HPGDS | O60760 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | ACR | P10323 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970232 | 0.82 | ALPL (0.57) | ALPLMAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL1456726 | 0.81 | HPGDS (0.58) | ALPLMAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL1007015 | 0.81 | MAPK1 (0.61) | ALPLMAPTRAB9ANPC1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28348020 | 0.81 | ALPL (0.56) | ALPLMAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL21630583 | 0.80 | MAPK1 (0.65) | ALPLMAPTRAB9ANPC1HPGDS | |
| SCHEMBL23500795 | 0.80 | ALPL (0.56) | ALPLMAPTRAB9ANPC1L3MBTL1 | |
| Ethane SCHEMBL6614658 | 0.79 | MAPK1 (0.59) | ALPLMAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL1430763 | 0.79 | ALPL (0.55) | ALPLMAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL4311802 | 0.79 | ALPL (0.55) | ALPLMAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL23212271 | 0.79 | ALPL (0.55) | ALPLMAPTRAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4655069-A1 | PYRIDAZINES AS SARM1 INHIBITORS | Disarm Therapeutics, Inc. (US) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024158775-A1 | PYRIDAZINES AS SARM1 INHIBITORS | DISARM THERAPEUTICS, INC. (US) | 2024-08-02 | — | — | WO | disclosed |
| CN-106187894-A | The preparation method of 1 methyl 3 ethyl 4 chlorine 5 pyrazole carboxylic acid ethyl ester | 潍坊鑫诺化工有限公司 | 2016-12-07 | — | — | CN | disclosed |