Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2659189 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1HPGDALOX12CHEK1 | |
| SCHEMBL1356289 | 0.72 | NPSR1 (0.56) | CHEK1MEN1KMT2ARGS12USP2 | |
| Butane SCHEMBL11876142 | 0.70 | MEN1 (0.65) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28495677 | 0.67 | MEN1 (0.60) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL22078662 | 0.66 | KDM4E (0.48) | KDM4EALDH1A1HPGDALOX12CHEK1 | |
| SCHEMBL27371589 | 0.65 | AR (0.46) | KDM4EALDH1A1HPGDALOX12CHEK1 | |
| SCHEMBL30517110 | 0.65 | POLB (0.62) | KDM4EALDH1A1MEN1KMT2ARGS12 | |
| SCHEMBL1888975 | 0.65 | POLB (0.62) | KDM4EALDH1A1MEN1KMT2ARGS12 | |
| SCHEMBL11435038 | 0.65 | ATG4B (0.49) | ALDH1A1ATG4BMEN1KMT2APOLB | |
| SCHEMBL11447330 | 0.64 | MEN1 (0.49) | KDM4EALDH1A1ATG4BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103948595-B | Acid imide position or 4-position substituted 1,8-naphthalimide derivative is as the purposes of PARP inhibitor | 华侨大学 | 2017-01-04 | — | — | CN | disclosed |