Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10296110 | 0.94 | — | — | |
| SCHEMBL21370739 | 0.78 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL22224179 | 0.78 | — | — | |
| SCHEMBL31008663 | 0.77 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL8854171 | 0.76 | TSHR (0.35) | ALDH1A1 | |
| SCHEMBL6944083 | 0.74 | — | — | |
| SCHEMBL19185637 | 0.74 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL27848911 | 0.74 | TSHR (0.40) | — | |
| SCHEMBL8854153 | 0.74 | TSHR (0.40) | — | |
| SCHEMBL9213660 | 0.74 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117564-B | A kind of preparation method of the highly resistance chamotte mould cement dispersants of graft esterification cationic side chain | 北京工业大学 | 2019-03-22 | — | — | CN | claimed |
| CN-107501476-A | A kind of preparation method of photo-crosslinking antibiotic property composite membrane of polyvinyl alcohol | 江南大学 | 2017-12-22 | — | — | CN | claimed |
| CN-106117564-A | A kind of preparation method of the height anti-chamotte mould cement dispersants of graft esterification cationic side chain | 北京工业大学 | 2016-11-16 | — | — | CN | claimed |