Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11687409 | 1.00 | LMNA (0.54) | LMNAKDM4EL3MBTL1HSD11B1AOC3 | |
| SCHEMBL28748813 | 0.82 | GRIA4 (0.40) | LMNAKDM4EHSD11B1ALDH1A1MAPT | |
| SCHEMBL28748969 | 0.82 | GRIA4 (0.40) | LMNAKDM4EHSD11B1ALDH1A1MAPT | |
| SCHEMBL2488308 | 0.81 | LMNA (0.50) | LMNAKDM4EL3MBTL1HSD11B1AOC3 | |
| SCHEMBL7875002 | 0.81 | LMNA (0.50) | LMNAKDM4EL3MBTL1HSD11B1AOC3 | |
| SCHEMBL13881582 | 0.80 | HTR2A (0.43) | LMNAALDH1A1POLBTDP1CYP2C19 | |
| SCHEMBL28748965 | 0.80 | AOC3 (0.49) | LMNAKDM4EHSD11B1AOC3KMT2A | |
| SCHEMBL28748880 | 0.80 | CYP1A2 (0.40) | LMNAKDM4EHSD11B1KMT2A | |
| SCHEMBL28748876 | 0.80 | CYP1A2 (0.40) | LMNAKDM4EHSD11B1KMT2A | |
| SCHEMBL28748869 | 0.80 | AOC3 (0.49) | LMNAKDM4EHSD11B1AOC3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083758-A | A kind of high-efficiency synthesis method of Mirabegron | 河南师范大学 | 2016-11-09 | — | — | CN | claimed |
| CN-114540321-B | Preparation method of R-2-sulfonyl-1-phenylethanol derivative | 沈阳药科大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-114540321-A | Preparation method of R-2-sulfonyl-1-phenylethanol derivative | 沈阳药科大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-106083758-A | A kind of high-efficiency synthesis method of Mirabegron | 河南师范大学 | 2016-11-09 | — | — | CN | disclosed |