Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488308 | 1.00 | LMNA (0.50) | LMNAALDH1A1KDM4EL3MBTL1HSD11B1 | |
| SCHEMBL10638198 | 0.98 | LMNA (0.48) | LMNAALDH1A1KDM4EL3MBTL1HSD11B1 | |
| Sulfuric Acid SCHEMBL27672617 | 0.85 | LMNA (0.48) | LMNAALDH1A1KDM4EL3MBTL1HSD11B1 | |
| SCHEMBL10634840 | 0.85 | RIPK1 (0.44) | LMNAALDH1A1KDM4EL3MBTL1HSD11B1 | |
| Sulfuric Acid SCHEMBL28213387 | 0.83 | AOC3 (0.47) | LMNAALDH1A1KDM4EL3MBTL1HSD11B1 | |
| SCHEMBL2935549 | 0.82 | SRC (0.48) | LMNAALDH1A1KDM4EHSD11B1SRC | |
| SCHEMBL28111816 | 0.81 | LMNA (0.54) | LMNAALDH1A1KDM4EL3MBTL1HSD11B1 | |
| SCHEMBL11687409 | 0.81 | LMNA (0.54) | LMNAALDH1A1KDM4EL3MBTL1HSD11B1 | |
| SCHEMBL1859129 | 0.80 | GABBR2 (0.52) | LMNAALDH1A1KDM4EHSD11B1SRC | |
| SCHEMBL11644157 | 0.79 | LMNA (0.52) | LMNAALDH1A1KDM4EL3MBTL1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326512-B1 | HYDROGENATION A B-KETOSULFONIC ACID COMPOUND | PRESIDENT OF NAGOYA UNIVERSITY (JP) | 2001-12-04 | — | — | US | disclosed |