Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 13/20 | 0.46 |
| ▸ | GCK | P35557 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2981817 | 0.81 | DAO (0.49) | DAORIPK1GCKCCNB2CDK1 | |
| SCHEMBL24076503 | 0.81 | DAO (0.53) | DAORIPK1GCKCCNB2CDK1 | |
| SCHEMBL29460593 | 0.79 | DAO (0.50) | DAORIPK1GCKCCNB2CDK1 | |
| SCHEMBL8135643 | 0.79 | RIPK1 (0.47) | DAORIPK1GCKCCNB2CDK1 | |
| SCHEMBL8134947 | 0.79 | DAO (0.46) | DAORIPK1GCKCCNB2CDK1 | |
| SCHEMBL23134497 | 0.79 | DAO (0.50) | DAORIPK1GCKCCNB2CDK1 | |
| SCHEMBL31660957 | 0.76 | RIPK1 (0.49) | DAORIPK1GCKCCNB2CDK1 | |
| SCHEMBL29588280 | 0.75 | DAO (0.46) | DAORIPK1GCKCCNB2CDK1 | |
| SCHEMBL19121174 | 0.75 | GCK (0.43) | DAORIPK1GCKCCNB2CDK1 | |
| SCHEMBL27984199 | 0.75 | DAO (0.53) | DAORIPK1CCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106470993-B | The azepine quinazoline inhibitor of Atypical protein kinase C | 癌症研究科技有限公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-106470993-A | The azepine quinazoline inhibitor of Atypical protein kinase C | 癌症研究科技有限公司 | 2017-03-01 | — | — | CN | disclosed |