Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 11/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | GCK | P35557 | 4/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2981817 | 0.86 | DAO (0.49) | RIPK1DAOGCKCCNB2CDK1 | |
| SCHEMBL29460593 | 0.83 | DAO (0.50) | RIPK1DAOGCKCCNB2CDK1 | |
| SCHEMBL23134497 | 0.83 | DAO (0.50) | RIPK1DAOGCKCCNB2CDK1 | |
| SCHEMBL8134947 | 0.83 | DAO (0.46) | RIPK1DAOGCKCCNB2CDK1 | |
| SCHEMBL31660957 | 0.80 | RIPK1 (0.49) | RIPK1DAOGCKCCNB2CDK1 | |
| SCHEMBL19121174 | 0.79 | GCK (0.43) | RIPK1DAOGCKCCNB2CDK1 | |
| SCHEMBL28111965 | 0.79 | DAO (0.49) | RIPK1DAOGCKCCNB2CDK1 | |
| SCHEMBL24076503 | 0.79 | DAO (0.53) | RIPK1DAOGCKCCNB2CDK1 | |
| SCHEMBL17601449 | 0.78 | DAO (0.56) | RIPK1DAOCCNB2CDK1CCNB1 | |
| SCHEMBL17601450 | 0.78 | DAO (0.56) | RIPK1DAOCCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737685-B1 | Pyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-07-19 | — | — | EP | disclosed |
| EP-0737685-A1 | Pyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-10-16 | — | — | EP | disclosed |