Quinoline

Quinoline

SCHEMBL28112007

C(=Cc1cc(-c2ccccc2)[nH]n1)c1ccccc1.c1ccc2ncccc2c1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.46
RAB9A P51151 6/20 0.46
NPC1 O15118 5/20 0.46
LMNA P02545 3/20 0.46
PKM P14618 1/20 0.46
PDGFRB P09619 1/20 0.44
PDGFRA P16234 1/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPT P10636 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
CASP3 P42574 1/20 0.41
ATM Q13315 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
HPGD P15428 3/20 0.40
CYP1A2 P05177 1/20 0.40
POLB P06746 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
GRM4 Q14833 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL27520741 0.78 ALDH1A1 (0.71) KDM4ERAB9ANPC1LMNAPKM
Quinoline SCHEMBL27772291 0.77 RAB9A (0.59) KDM4ERAB9ANPC1LMNAPKM
Quinoline SCHEMBL28850584 0.75 RAB9A (0.81) KDM4ERAB9ANPC1LMNAPKM
Quinoline SCHEMBL28771536 0.72 RAB9A (0.43) KDM4ERAB9ANPC1LMNAPKM
Quinoline SCHEMBL27697533 0.70 SCN4A (0.67) KDM4ERAB9ANPC1LMNAALDH1A1
Biphenyl SCHEMBL4922682 0.70 ALDH1A1 (0.81) KDM4ERAB9ANPC1PDGFRBPDGFRA
Quinoline SCHEMBL27594824 0.70 ALDH1A1 (0.90) KDM4ERAB9ANPC1LMNAPDGFRB
Quinoline SCHEMBL28207963 0.70 ALDH1A1 (0.61) KDM4ERAB9ANPC1LMNAPKM
SCHEMBL26633988 0.70 NPC1 (0.76) KDM4ERAB9ANPC1LMNAPDGFRB
SCHEMBL3031765 0.69 KDM4E (0.43) KDM4ERAB9ANPC1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104133343-B Photosensitive polymer combination, photosensitive element, the forming method of photoresist figure and the manufacture method of printed circuit board (PCB) 日立化成株式会社 2016-11-16 CN disclosed