SCHEMBL2811206

SCHEMBL2811206

O=C(Nc1ccccc1)C(=CSc1ccccc1)c1ccsc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.55
KCNK3 O14649 1/20 0.46
KCNK9 Q9NPC2 1/20 0.46
ALDH1A1 P00352 2/20 0.44
HTT P42858 2/20 0.44
LMNA P02545 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
ELANE P08246 1/20 0.40
GAA P10253 1/20 0.40
ALOX12 P18054 1/20 0.40
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
DAO P14920 1/20 0.39
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2811204 1.00 HPGD (0.55) HPGDKCNK3KCNK9ALDH1A1HTT
SCHEMBL2811124 0.92 HPGD (0.49) HPGDKCNK3KCNK9ALDH1A1HTT
SCHEMBL2811122 0.92 HPGD (0.49) HPGDKCNK3KCNK9ALDH1A1HTT
SCHEMBL2808703 0.84 LMNA (0.61) HPGDALDH1A1HTTLMNAKMT2A
SCHEMBL2808706 0.84 LMNA (0.61) HPGDALDH1A1HTTLMNAKMT2A
SCHEMBL2811434 0.83 LCK (0.46) HPGDKCNK3KCNK9ALDH1A1HTT
SCHEMBL2811436 0.83 LCK (0.46) HPGDKCNK3KCNK9ALDH1A1HTT
SCHEMBL2815445 0.80 HPGD (0.42) HPGDKCNK3KCNK9ALDH1A1HTT
SCHEMBL3041499 0.80 HPGD (0.42) HPGDKCNK3KCNK9ALDH1A1HTT
SCHEMBL2815447 0.80 HPGD (0.42) HPGDKCNK3KCNK9ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278473-B2 Alpha, beta-unsaturated imidate compound and pesticidal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-02 US disclosed
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-23 US disclosed
WO-2009064031-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-22 WO disclosed
WO-2009064031-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME OXER1, CBR1, DEGS1 HPGD 2145/4885KCNK3 2683/4885KCNK9 3087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.