SCHEMBL3041499

SCHEMBL3041499

COC(=O)/C(=C\Sc1ccccc1)c1ccsc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.42
LCK P06239 1/20 0.40
FYN P06241 1/20 0.40
DAO P14920 1/20 0.40
KCNK3 O14649 1/20 0.38
KCNK9 Q9NPC2 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
PLAU P00749 1/20 0.38
ELANE P08246 1/20 0.38
HDAC1 Q13547 1/20 0.37
GPR52 Q9Y2T5 1/20 0.36
HSD11B1 P28845 1/20 0.36
ALDH1A1 P00352 3/20 0.35
HTT P42858 2/20 0.35
GAA P10253 1/20 0.35
ALOX12 P18054 1/20 0.35
PLIN1 O60240 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2815445 1.00 HPGD (0.42) HPGDLCKFYNDAOKCNK3
SCHEMBL2815447 1.00 HPGD (0.42) HPGDLCKFYNDAOKCNK3
SCHEMBL2813477 0.87 MEN1 (0.42) HPGDLCKFYNDAOCES2
SCHEMBL2813475 0.87 MEN1 (0.42) HPGDLCKFYNDAOCES2
SCHEMBL2811436 0.84 LCK (0.46) HPGDLCKFYNDAOKCNK3
SCHEMBL2811434 0.84 LCK (0.46) HPGDLCKFYNDAOKCNK3
SCHEMBL2808184 0.84 ALDH1A1 (0.45) HPGDALDH1A1HTTGAAPLIN1
SCHEMBL12851372 0.84 ALDH1A1 (0.45) HPGDALDH1A1HTTGAAPLIN1
SCHEMBL2808186 0.84 ALDH1A1 (0.45) HPGDALDH1A1HTTGAAPLIN1
SCHEMBL2811206 0.80 HPGD (0.55) HPGDLCKFYNDAOKCNK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8318981-B2 Imidate compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-11-27 US disclosed
US-20100210683-A1 IMIDATE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210683-A1 IMIDATE COMPOUND AND USE THEREOF FOR PEST CONTROL CYP1A1, CYC1, C1S HPGD 2588/4885LCK 4118/4885FYN 4476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.