Chlorobenzene

Chlorobenzene

SCHEMBL28112104

Clc1ccc2ccccc2c1.Clc1ccc2ccccc2c1.Clc1cccc2ccccc12.Clc1ccccc1

nearest known ligand 0.61

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.61
CYP2A6 P11509 5/20 0.61
FADS1 O60427 1/20 0.44
CYP1A1 P04798 4/20 0.40
CYP1B1 Q16678 4/20 0.40
TSHR P16473 2/20 0.39
KDM1A O60341 1/20 0.38
RCOR1 Q9UKL0 1/20 0.38
GRIK1 P39086 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
PTGES O14684 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8208536 0.94 CYP2A6 (0.68) CYP1A2CYP2A6FADS1CYP1A1CYP1B1
SCHEMBL145859 0.94 CYP2A6 (0.68) CYP1A2CYP2A6FADS1CYP1A1CYP1B1
Methyl Alcohol SCHEMBL28240100 0.89 CYP2A6 (0.61) CYP1A2CYP2A6FADS1CYP1B1TSHR
Phenol SCHEMBL6410569 0.88 CYP2A6 (0.55) CYP1A2CYP2A6TSHRGRIK1LMNA
Chlorobenzene SCHEMBL22529164 0.87 CYP2A6 (0.81) CYP1A2CYP2A6FADS1TSHRLMNA
Acetone SCHEMBL28077025 0.85 CYP2A6 (0.55) CYP1A2CYP2A6CYP1A1CYP1B1GRIK1
Chlorobenzene SCHEMBL20479175 0.84 CYP2A6 (0.85) CYP1A2CYP2A6TSHRGRIK1LMNA
Dimethylformamide SCHEMBL28302419 0.81 CYP2A6 (0.50) CYP1A2CYP2A6FADS1CYP1A1CYP1B1
Naphthalene SCHEMBL8141546 0.80 CYP2A6 (0.94) CYP1A2CYP2A6CYP1B1TSHRLMNA
Benzene SCHEMBL1286405 0.80 CYP2A6 (0.94) CYP1A2CYP2A6CYP1B1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103402636-B Manufacture the method for modified metal cyclopentadienyl catalyst, the catalyst made and application thereof 格雷斯公司 2016-12-14 CN disclosed