Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.60 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL29010404 | 1.00 | — | — | |
| Bicarbonate SCHEMBL28582066 | 0.94 | CA4 (0.67) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL1331459 | 0.94 | — | — | |
| Bicarbonate SCHEMBL8388552 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1331273 | 0.94 | — | — | |
| Bicarbonate SCHEMBL29061109 | 0.94 | CA4 (0.67) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL33315 | 0.94 | CA4 (0.50) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL25 | 0.94 | — | — | |
| Bicarbonate SCHEMBL2121875 | 0.94 | CA4 (0.67) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL714912 | 0.94 | CA4 (0.67) | CA4FAHD1CA1MEN1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117894983-A | Non-metallic element double-coordination doped carbon-based material and preparation method and application thereof | 暨南大学 | 2024-04-16 | — | — | CN | claimed |
| CN-113834709-B | Plasma mass spectrum/spectrum determination method for enriching noble metals in geological sample by bismuth test | 中国地质科学院矿产综合利用研究所 | 2023-06-30 | — | — | CN | claimed |
| CN-114759188-B | Potassium ion battery negative electrode material and preparation method and application thereof | 暨南大学 | 2022-09-06 | — | — | CN | claimed |
| CN-114759188-A | Potassium ion battery negative electrode material and preparation method and application thereof | 暨南大学 | 2022-07-15 | — | — | CN | claimed |
| CN-117894983-B | Non-metallic element double-coordination doped carbon-based material and preparation method and application thereof | 暨南大学 | 2024-10-08 | — | — | CN | disclosed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-117894983-A | Non-metallic element double-coordination doped carbon-based material and preparation method and application thereof | 暨南大学 | 2024-04-16 | — | — | CN | disclosed |
| CN-117736207-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-115362003-B | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-113834709-B | Plasma mass spectrum/spectrum determination method for enriching noble metals in geological sample by bismuth test | 中国地质科学院矿产综合利用研究所 | 2023-06-30 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| CN-114759188-B | Potassium ion battery negative electrode material and preparation method and application thereof | 暨南大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-114759188-A | Potassium ion battery negative electrode material and preparation method and application thereof | 暨南大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-106082996-A | A kind of bismuthino optical-thermal conversion material and preparation method thereof | 华南理工大学 | 2016-11-09 | — | — | CN | disclosed |