Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 13/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.47 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058979 | 0.88 | PARP10 (0.51) | PARP10SMN1; SMN2NPC1RAB9APARP4 | |
| SCHEMBL27440211 | 0.83 | PARP10 (0.65) | PARP10PARP4CA1CA2PARP1 | |
| SCHEMBL9639855 | 0.83 | TP53 (0.54) | CA1CA2KMT2AMAPK1 | |
| SCHEMBL9732746 | 0.83 | TAS1R3 (0.40) | SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL10784950 | 0.81 | TP53 (0.60) | KMT2A | |
| SCHEMBL9061850 | 0.80 | PARP10 (0.53) | PARP10SMN1; SMN2NPC1RAB9APARP4 | |
| SCHEMBL5915075 | 0.79 | TP53 (0.62) | KMT2A | |
| SCHEMBL25788016 | 0.79 | TP53 (0.62) | KMT2A | |
| SCHEMBL10514724 | 0.79 | RARB (0.57) | KMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL27639615 | 0.79 | ELANE (0.50) | SMN1; SMN2RAB9AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106278775-A | The preparation method of a kind of arylamides and purification method thereof | 温州大学 | 2017-01-04 | — | — | CN | disclosed |