Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9061631 | 0.87 | TP53 (0.60) | KMT2AMEN1TP53TSHRPLA2G4B | |
| SCHEMBL3626125 | 0.85 | TP53 (0.58) | KMT2AMAPK1TP53TSHRPLA2G4B | |
| SCHEMBL9058979 | 0.84 | PARP10 (0.51) | PARP10KMT2AMEN1APAF1RGS12 | |
| SCHEMBL10295292 | 0.84 | MGLL (0.56) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27868074 | 0.83 | ELANE (0.49) | MAPK1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL6261663 | 0.83 | RARB (0.63) | KMT2AMEN1TP53TSHRPLA2G4B | |
| SCHEMBL18264279 | 0.83 | ELANE (0.49) | MAPK1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL8925288 | 0.83 | ELANE (0.49) | MAPK1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL6827554 | 0.82 | TSHR (0.45) | MAPK1SMN1; SMN2TP53TSHRPLA2G4B | |
| SCHEMBL28112451 | 0.80 | PARP10 (0.57) | PARP10KMT2AMEN1APAF1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017589-A1 | METHOD OF SMOOTHING OR REMOVING WRINKLES AND METHOD OF STIMULATING COLLAGEN SYNTHESIS | KAO CORPORATION (JP) | 1996-06-13 | — | — | WO | disclosed |