Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383033 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL32667958 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| Formic Acid Methyl Ester SCHEMBL28113321 | 0.81 | MAPT (0.54) | KDM4EALDH1A1SMN1; SMN2HSD17B10TP53 | |
| Formic Acid Methyl Ester SCHEMBL28113328 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| Formamide SCHEMBL28166010 | 0.76 | KDM4E (0.66) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL30160092 | 0.75 | KDM4E (0.73) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL104598 | 0.75 | KDM4E (0.73) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL7402531 | 0.73 | KDM4E (0.71) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL14156164 | 0.73 | SMN1; SMN2 (0.74) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPT | |
| Iodide SCHEMBL8569085 | 0.73 | KDM4E (0.71) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083849-A | The quaternary condensed or five-membered ring pyrido phthalazone compounds as PARP inhibitor | 百济神州有限公司 | 2016-11-09 | — | — | CN | disclosed |