Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27891548 | 0.87 | TRPM4 (0.35) | TRPM4ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL27908453 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HSD17B10CYP1A2HPGDCYP2A6 | |
| SCHEMBL28113028 | 0.79 | L3MBTL1 (0.38) | TRPM4ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL27891536 | 0.68 | CYP2A6 (0.42) | ALDH1A1HSD17B10HIF1ACYP1A2CYP2A6 | |
| SCHEMBL27891576 | 0.68 | ALDH1A1 (0.43) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL28133818 | 0.67 | TRPM4 (0.46) | TRPM4ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL27891609 | 0.67 | TRPM4 (0.35) | TRPM4ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL2885129 | 0.67 | TRPM4 (0.38) | TRPM4ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL28112966 | 0.65 | TAAR1 (0.38) | ALDH1A1TSHRPKMTAAR1MAPK1 | |
| SCHEMBL28694544 | 0.64 | TRPM4 (0.43) | TRPM4ALDH1A1HSD17B10CYP1B1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947319-B | Method and tertiary phosphine for phosphine oxides is reduced into corresponding tertiary phosphine in the presence of a catalyst is used for reducing in the presence of a catalyst the purposes of phosphine oxides | 克罗马福拉公司 | 2016-11-09 | — | — | CN | disclosed |