Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | AHCY | P23526 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28145519 | 0.92 | ADORA2A (0.50) | GSK3BADCY5ALDH1A1ADORA2AADORA1 | |
| Sulfuric Acid SCHEMBL10790466 | 0.85 | GSK3B (0.46) | GSK3BADCY5ALDH1A1ADORA2AADORA1 | |
| SCHEMBL15297006 | 0.85 | ADCY5 (0.47) | GSK3BADCY5ALDH1A1ADORA2AADORA1 | |
| SCHEMBL14125909 | 0.83 | ADORA2A (0.51) | GSK3BALDH1A1ADORA2AADORA1PI4KA | |
| SCHEMBL28406876 | 0.82 | ADORA2A (0.50) | GSK3BALDH1A1ADORA2AADORA1PI4KA | |
| SCHEMBL16485904 | 0.82 | GSK3B (0.48) | GSK3BALDH1A1ADORA2AADORA1PI4KA | |
| SCHEMBL28086747 | 0.79 | ADORA2A (0.48) | GSK3BADCY5ALDH1A1ADORA2AADORA1 | |
| SCHEMBL28406873 | 0.77 | ADORA2A (0.50) | GSK3BALDH1A1ADORA2AADORA1PI4KA | |
| SCHEMBL385843 | 0.77 | ADORA2A (0.55) | GSK3BADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1577868 | 0.76 | ADORA2A (0.46) | GSK3BALDH1A1ADORA2AADORA1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146561-A | A kind of synthetic method of tenofovir | 浙江九洲药业股份有限公司 | 2016-11-23 | — | — | CN | claimed |
| CN-107737335-B | Microbubble complexes and methods of use | 通用电气公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-114617868-A | NRF2 activating compounds and uses thereof | 参宿七制药股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-108699011-B | NRF2 activating compounds and uses thereof | 参宿七制药股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-106573901-B | Fumarate analogues and their use in the treatment of autoimmune or inflammatory diseases | 参宿七制药股份有限公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-108699034-B | NRF2 activating compounds and uses thereof | 参宿七制药股份有限公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-112004808-A | Prodrugs of NRF 2-activating compounds and uses thereof | 参宿七制药股份有限公司 | 2020-11-27 | — | — | CN | disclosed |
| CN-106146561-A | A kind of synthetic method of tenofovir | 浙江九洲药业股份有限公司 | 2016-11-23 | — | — | CN | disclosed |