Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880080 | 0.66 | CA12 (0.34) | MAPTMITFNSD2ALDH1A1LMNA | |
| SCHEMBL2531942 | 0.63 | MAOA (0.58) | MAPTMITFNSD2ALDH1A1LMNA | |
| SCHEMBL30587670 | 0.63 | MAOA (0.58) | MAPTMITFNSD2ALDH1A1LMNA | |
| SCHEMBL10883313 | 0.61 | KMT2A (0.49) | MAPTMITFNSD2ALDH1A1LMNA | |
| SCHEMBL20567610 | 0.61 | ALDH1A1 (0.37) | MAPTMITFNSD2ALDH1A1LMNA | |
| SCHEMBL28880084 | 0.60 | HPGD (0.35) | MITFNSD2ALDH1A1LMNACASP3 | |
| SCHEMBL8958929 | 0.60 | CA12 (0.36) | MITFNSD2ALDH1A1LMNACASP3 | |
| SCHEMBL10613039 | 0.60 | ALDH1A1 (0.36) | MAPTMITFNSD2ALDH1A1LMNA | |
| SCHEMBL11617598 | 0.58 | CA12 (0.34) | MAPTMITFNSD2ALDH1A1LMNA | |
| SCHEMBL14233618 | 0.58 | ALDH1A1 (0.41) | MAPTMITFNSD2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146367-B | Allyl sulfenyl amino 1,4-benzoquinone class compound, it is prepared and application | 北京大学 | 2017-12-26 | — | — | CN | disclosed |
| CN-106146367-A | Allyl sulfenyl amino 1,4-benzoquinone compounds, its preparation and application | 北京大学 | 2016-11-23 | — | — | CN | disclosed |