Acridine

Acridine

SCHEMBL28113323

COC=O.c1ccc2nc3ccccc3cc2c1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.62
HPGD P15428 4/20 0.62
MAPT P10636 3/20 0.62
GLA P06280 2/20 0.62
ACHE P22303 1/20 0.62
GAA P10253 3/20 0.47
TLR8 Q9NR97 2/20 0.47
HTR3A P46098 1/20 0.47
KDM4E B2RXH2 5/20 0.46
NQO2 P16083 5/20 0.45
POLB P06746 4/20 0.42
KMT2A Q03164 4/20 0.42
LMNA P02545 3/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MEN1 O00255 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
STAT3 P40763 1/20 0.42
PTBP1 P26599 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenazine SCHEMBL28567771 0.87 MAPT (0.55) ALDH1A1HPGDMAPTGLAACHE
Anthracene SCHEMBL32670790 0.84 CYP2A6 (0.46) ALDH1A1HPGDMAPTKDM4ENQO2
Formic Acid Methyl Ester SCHEMBL22041914 0.82 GPBAR1 (0.45) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL29114524 0.80 ALDH1A1 (0.71) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL27860754 0.80 ALDH1A1 (0.71) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL27450140 0.80 ALDH1A1 (0.71) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL1772714 0.79 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL29352289 0.79 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL3045498 0.79 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL8339 0.79 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574095-A Double-band acridine formate anthracene methyl ester photocatalyst and preparation method and application thereof 江西初源新材料有限公司 2026-02-27 CN claimed
CN-107973749-A Nitrogen anthracene compound and its synthetic method and application 华东师范大学 2018-05-01 CN claimed
CN-121574095-A Double-band acridine formate anthracene methyl ester photocatalyst and preparation method and application thereof 江西初源新材料有限公司 2026-02-27 CN disclosed
CN-106083849-A The quaternary condensed or five-membered ring pyrido phthalazone compounds as PARP inhibitor 百济神州有限公司 2016-11-09 CN disclosed