Formic Acid Methyl Ester

Formic Acid Methyl Ester

SCHEMBL28113348

COC=O.NCC1CCNCC1

nearest known ligand 0.35

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
NCF1 P14598 1/20 0.34
GABRA5 P31644 3/20 0.34
SLC6A1 P30531 2/20 0.34
GABRB2 P47870 2/20 0.34
SLC6A12 P48065 2/20 0.34
SLC6A11 P48066 2/20 0.34
SLC6A13 Q9NSD5 2/20 0.34
GABRA1 P14867 2/20 0.34
GABRR1 P24046 1/20 0.34
GABRA4 P48169 1/20 0.34
ANPEP P15144 1/20 0.34
ERAP2 Q6P179 1/20 0.34
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
LMNA P02545 2/20 0.32
PLG P00747 1/20 0.32
PLAT P00750 1/20 0.32
ALOX15 P16050 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid Methyl Ester SCHEMBL28113386 0.89 SLC6A1 (0.44) TDP1GABRA5SLC6A1GABRB2SLC6A12
Formic Acid Methyl Ester SCHEMBL28112840 0.87 SLC6A1 (0.43) TDP1GABRA5SLC6A1GABRB2SLC6A12
Tert-Butyl Formate SCHEMBL27663311 0.82 TDP1 (0.45) TDP1NCF1GABRA5SLC6A1GABRB2
Tert-Butyl Formate SCHEMBL27765046 0.80 TDP1 (0.43) TDP1GABRA5SLC6A1GABRB2SLC6A12
SCHEMBL134511 0.80
Formic Acid Methyl Ester SCHEMBL28096801 0.79 NCF1 (0.37) NCF1LMNAPLGPLAT
Formic Acid Methyl Ester SCHEMBL28113365 0.78 EED (0.38) GABRA5SLC6A1GABRB2SLC6A12SLC6A11
Hydrochloric Acid SCHEMBL2674811 0.78
Iodide SCHEMBL31297046 0.78
Hydrochloric Acid SCHEMBL4716511 0.78 NCF1 (0.40) TDP1NCF1GABRA5SLC6A1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106188027-A Heteroaromatic analog derivative and the application in medicine thereof 广东东阳光药业有限公司 2016-12-07 CN disclosed