SCHEMBL28113677

SCHEMBL28113677

N#Cc1ccccc1C(=O)NN

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPIA P62937 1/20 0.50
CTSD P07339 2/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
HDAC3 O15379 1/20 0.48
HDAC1 Q13547 1/20 0.48
ALDH1A1 P00352 2/20 0.47
POLB P06746 2/20 0.46
LMNA P02545 2/20 0.45
GAA P10253 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MITF O75030 1/20 0.44
NCOA1 Q15788 1/20 0.44
NCOA3 Q9Y6Q9 1/20 0.44
P2RX7 Q99572 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19547945 0.84 CTSD (0.41) PPIACTSDCA1CA2CA9
SCHEMBL6461738 0.82 CTSD (0.50) CTSDCA1CA2CA9ALDH1A1
SCHEMBL21906758 0.81 PPIA (0.50) PPIAHDAC3HDAC1ALDH1A1POLB
SCHEMBL6970508 0.81 PPIA (0.50) PPIAHDAC3HDAC1ALDH1A1POLB
SCHEMBL18247810 0.81 CTSD (0.49) CTSDCA1CA2CA9ALDH1A1
SCHEMBL29732828 0.81 CTSD (0.49) CTSDCA1CA2CA9ALDH1A1
SCHEMBL2728048 0.81 POLB (0.67) PPIAHDAC3HDAC1ALDH1A1POLB
SCHEMBL9489936 0.79 HDAC3 (0.67) PPIAHDAC3HDAC1POLBSMN1; SMN2
SCHEMBL239328 0.79 CTSD (0.63) CTSDCA1CA2CA9ALDH1A1
SCHEMBL30547074 0.79 CTSD (0.63) CTSDCA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113264820-B Method for preparing ketone compound from olefin 江苏大学 2022-10-28 CN disclosed
CN-113717037-A Green synthesis method of 2, 5-dimethoxybenzaldehyde 镇江中智化学科技有限公司 2021-11-30 CN disclosed
CN-106146347-B A kind of Low-molecular weight organogel factor and preparation method and organogel 深圳大学 2017-12-26 CN disclosed
CN-107394139-A Composite lithium battery positive electrode material and preparation method thereof, lithium battery positive electrode and lithium battery 东莞中汽宏远汽车有限公司 2017-11-24 CN disclosed
CN-106146347-A A kind of Low-molecular weight organogel factor and preparation method and organogel 深圳大学 2016-11-23 CN disclosed