Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28113677 | 0.81 | PPIA (0.50) | PPIAPOLBLMNAALDH1A1KAT6A | |
| SCHEMBL21906758 | 0.81 | PPIA (0.50) | PPIAPOLBLMNAALDH1A1KAT6A | |
| SCHEMBL2728048 | 0.81 | POLB (0.67) | PPIAPOLBLMNAALDH1A1KAT6A | |
| SCHEMBL2164376 | 0.79 | PPIA (0.44) | PPIAPOLBLMNAALDH1A1KAT6A | |
| SCHEMBL28901051 | 0.78 | LMNA (0.70) | POLBLMNAALDH1A1MEN1MAPT | |
| SCHEMBL515447 | 0.78 | PPIA (0.43) | PPIAPOLBLMNAALDH1A1KAT6A | |
| SCHEMBL31000747 | 0.77 | PPIA (0.45) | PPIAPOLBLMNAALDH1A1KAT6A | |
| SCHEMBL2913776 | 0.77 | ALDH1A1 (0.45) | PPIAPOLBLMNAALDH1A1KAT6A | |
| SCHEMBL6276445 | 0.77 | PPIA (0.45) | PPIAPOLBLMNAALDH1A1KAT6A | |
| SCHEMBL20324936 | 0.77 | ALDH1A1 (0.69) | PPIAPOLBLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |