Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 3/20 | 0.45 |
| ▸ | JAK1 | P23458 | 3/20 | 0.45 |
| ▸ | JAK3 | P52333 | 3/20 | 0.45 |
| ▸ | TYK2 | P29597 | 2/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417065 | 0.78 | JAK2 (0.47) | HRH3PRKAA2OPRM1THRBUSP2 | |
| SCHEMBL23951352 | 0.77 | ACHE (0.49) | MEN1KMT2ACYP2D6ACHE | |
| SCHEMBL7238995 | 0.76 | HRH3 (0.65) | HRH3OPRM1THRBCCR2MEN1 | |
| SCHEMBL28024576 | 0.75 | KCNJ1 (0.66) | HRH3USP2CCR2FAAHMEN1 | |
| SCHEMBL20804360 | 0.75 | KCNJ1 (0.66) | HRH3USP2CCR2FAAHMEN1 | |
| SCHEMBL647375 | 0.75 | HRH3 (0.57) | HRH3PRKAA2OPRM1THRBUSP2 | |
| SCHEMBL70021 | 0.75 | HRH3 (0.56) | HRH3PRKAA2OPRM1THRBUSP2 | |
| SCHEMBL14375216 | 0.75 | HRH3 (0.67) | HRH3PRKAA2OPRM1THRBUSP2 | |
| Hydrochloric Acid SCHEMBL10625447 | 0.75 | HRH3 (0.64) | HRH3OPRM1THRBMEN1KMT2A | |
| SCHEMBL14163064 | 0.75 | HTT (0.42) | HRH3TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928211-A | Benzamide compound for treating dysbolism | 里格尔药品股份有限公司 | 2017-07-07 | — | — | CN | disclosed |
| CN-104016980-B | For treating the benzamide compound of dysbolismus | 里格尔药品股份有限公司 | 2016-12-07 | — | — | CN | disclosed |