SCHEMBL21887167

SCHEMBL21887167

COC1=C/C(=C2\C=CC(=O)C(OC)=C2)C=CC1=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERBB2 P04626 1/20 0.70
KDM4E B2RXH2 6/20 0.42
MAPT P10636 6/20 0.42
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
MAPK1 P28482 4/20 0.42
CYP3A4 P08684 4/20 0.42
TP53 P04637 3/20 0.42
USP2 O75604 3/20 0.42
HKDC1 Q2TB90 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PTPN1 P18031 1/20 0.38
IDO1 P14902 1/20 0.38
CDC25A P30304 1/20 0.38
CDC25B P30305 1/20 0.38
TDP1 Q9NUW8 3/20 0.36
PKM P14618 1/20 0.36
MCL1 Q07820 1/20 0.36
ALOX5 P09917 4/20 0.35
PTGS2 P35354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28856262 0.78 ERBB2 (0.59) ERBB2KDM4EMAPTMEN1KMT2A
SCHEMBL28113764 0.78 ERBB2 (0.91) ERBB2KDM4EMAPTMEN1KMT2A
SCHEMBL13302687 0.76 ERBB2 (0.64) ERBB2KDM4EMAPTMEN1KMT2A
SCHEMBL5214897 0.76 ERBB2 (0.64) ERBB2KDM4EMAPTMEN1KMT2A
SCHEMBL49737 0.75 ERBB2 (0.62) ERBB2KDM4EMAPTMEN1KMT2A
SCHEMBL12958410 0.73 ERBB2 (0.43) ERBB2KDM4EMAPTMEN1KMT2A
SCHEMBL28259188 0.73 ERBB2 (0.59) ERBB2KDM4EMAPTMEN1KMT2A
SCHEMBL197028 0.70 HKDC1 (0.70) ERBB2KDM4EMAPTMEN1KMT2A
SCHEMBL3417111 0.69 HKDC1 (0.56) ERBB2KDM4EMAPTMEN1KMT2A
SCHEMBL14414179 0.69 ERBB2 (0.53) ERBB2KDM4EMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096390-A1 AUTO-EXPRESSION BROTH AND USES THEREOF UNIVERSITY OF MONTANA (US) 2025-05-08 WO disclosed
US-11215935-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-01-04 US disclosed
US-11169455-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2021-11-09 US disclosed
US-20200341392-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2020-10-29 US disclosed
US-20200341393-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2020-10-29 US disclosed
US-10754266-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2020-08-25 US disclosed
US-20200096884-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO.,LTD. (JP) 2020-03-26 US disclosed