Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | NQO2 | P16083 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17502167 | 0.90 | MAPT (0.60) | MAPTNQO2GAAMGAMSI | |
| SCHEMBL1564958 | 0.87 | MAPT (0.57) | MAPTNQO2ALDH1A1TSHRGAA | |
| SCHEMBL18535210 | 0.76 | MAPT (0.83) | MAPTNQO2ALDH1A1TSHRNPC1 | |
| SCHEMBL1564292 | 0.76 | GAA (0.54) | MAPTNQO2ALDH1A1GAANPC1 | |
| SCHEMBL2937315 | 0.74 | MAPT (0.49) | MAPTNQO2GAANPC1POLB | |
| SCHEMBL18535211 | 0.72 | MAPT (0.65) | MAPTNQO2ALDH1A1TSHRNPC1 | |
| SCHEMBL25309375 | 0.71 | NQO2 (0.68) | MAPTNQO2ALDH1A1TSHRGAA | |
| SCHEMBL6592438 | 0.70 | GPR35 (0.51) | MAPTALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL7762455 | 0.70 | MAPT (0.61) | MAPTNQO2ALDH1A1TSHRGAA | |
| SCHEMBL2871982 | 0.70 | MAPT (0.57) | MAPTNQO2ALDH1A1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117188-B | Compounds for the treatment of cancer | 台北科技大学 | 2020-07-17 | — | — | CN | disclosed |
| CN-106117188-A | Compounds for the treatment of cancer | 台北科技大学 | 2016-11-16 | — | — | CN | disclosed |