Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | NQO2 | P16083 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18535210 | 0.84 | MAPT (0.83) | MAPTNQO2LMNANPC1RAB9A | |
| SCHEMBL7762455 | 0.78 | MAPT (0.61) | MAPTNQO2LMNANPC1RAB9A | |
| SCHEMBL12855186 | 0.78 | MAPT (0.61) | MAPTNQO2LMNANPC1RAB9A | |
| SCHEMBL28113797 | 0.72 | MAPT (0.69) | MAPTNQO2LMNANPC1RAB9A | |
| SCHEMBL17502167 | 0.70 | MAPT (0.60) | MAPTNQO2LMNACYP19A1TDP1 | |
| SCHEMBL17502192 | 0.70 | MAPT (0.60) | MAPTNQO2LMNANPC1RAB9A | |
| SCHEMBL10627274 | 0.68 | OPRK1 (0.56) | MAPTNQO2LMNANPC1RAB9A | |
| SCHEMBL1635157 | 0.68 | MAPT (0.49) | MAPTNQO2LMNANPC1RAB9A | |
| SCHEMBL2871982 | 0.68 | MAPT (0.57) | MAPTNQO2LMNANPC1RAB9A | |
| SCHEMBL441437 | 0.68 | MAPT (0.57) | MAPTNQO2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2083819-B1 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS | OMEROS CORP (US) | 2017-02-22 | — | — | EP | disclosed |