Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15239732 | 0.84 | GSK3B (0.54) | DRD4DRD2KMT2ASMN1; SMN2GSK3B | |
| SCHEMBL15239730 | 0.84 | GSK3B (0.54) | DRD4DRD2KMT2ASMN1; SMN2GSK3B | |
| SCHEMBL27588810 | 0.81 | KDM4E (0.50) | ADRA1AATMKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL28113204 | 0.80 | DRD4 (0.47) | DRD4ADRA1AATMKMT2ASMN1; SMN2 | |
| SCHEMBL6366383 | 0.80 | ALDH1A1 (0.46) | ADRA1AATMSMN1; SMN2GSK3BNPC1 | |
| SCHEMBL27554247 | 0.80 | ADRA1A (0.44) | ADRA1AATMKMT2ASMN1; SMN2GSK3B | |
| SCHEMBL6366201 | 0.80 | ALDH1A1 (0.46) | ADRA1AATMSMN1; SMN2GSK3BNPC1 | |
| SCHEMBL6366198 | 0.80 | ALDH1A1 (0.46) | ADRA1AATMSMN1; SMN2GSK3BNPC1 | |
| SCHEMBL29037833 | 0.80 | ERCC5 (0.46) | DRD4DRD2KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL363988 | 0.79 | ATM (0.47) | DRD4ATMKMT2ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083686-A | The method that α bromoacetophenone oxime ether synthesizes 2,4 diaryl pyrrole compounds | 苏州大学 | 2016-11-09 | — | — | CN | disclosed |