Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018274 | 0.87 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL14374929 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL14374313 | 0.82 | NPC1 (0.47) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL27548769 | 0.81 | GSK3B (0.49) | CYP1A2HPGDPARP1ATMSMN1; SMN2 | |
| SCHEMBL17986364 | 0.81 | GAA (0.41) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL17986363 | 0.81 | GAA (0.41) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL28113202 | 0.81 | DRD2 (0.47) | ALDH1A1KMT2ADRD4DRD2MAPT | |
| SCHEMBL15219740 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL15164587 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL2437354 | 0.80 | KMT2A (0.57) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083686-A | The method that α bromoacetophenone oxime ether synthesizes 2,4 diaryl pyrrole compounds | 苏州大学 | 2016-11-09 | — | — | CN | claimed |
| CN-106083686-A | The method that α bromoacetophenone oxime ether synthesizes 2,4 diaryl pyrrole compounds | 苏州大学 | 2016-11-09 | — | — | CN | disclosed |