⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887700 | 0.80 | ATAD2 (0.48) | — | |
| SCHEMBL6471984 | 0.77 | KDM3B (0.43) | — | |
| SCHEMBL30223399 | 0.64 | PARP1 (0.47) | — | |
| SCHEMBL31309025 | 0.64 | PARP1 (0.47) | — | |
| SCHEMBL25003360 | 0.63 | PDE2A (0.35) | — | |
| Thymine SCHEMBL4349890 | 0.63 | ATAD2 (0.76) | — | |
| SCHEMBL1918404 | 0.63 | ATAD2 (0.52) | — | |
| Hydrochloric Acid SCHEMBL31309105 | 0.62 | PDE2A (0.34) | — | |
| SCHEMBL15798699 | 0.60 | KDM4E (0.41) | — | |
| SCHEMBL8933555 | 0.60 | GAA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106170553-A | Modified nucleic acid molecules and uses thereof | 现代治疗公司 | 2016-11-30 | — | — | CN | claimed |
| CN-106170553-A | Modified nucleic acid molecules and uses thereof | 现代治疗公司 | 2016-11-30 | — | — | CN | disclosed |