SCHEMBL887700

SCHEMBL887700

CC(N)c1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ATAD2 Q6PL18 1/20 0.48
DPYD Q12882 5/20 0.43
MAPT P10636 3/20 0.43
GAA P10253 3/20 0.43
ALDH1A1 P00352 2/20 0.43
LMNA P02545 1/20 0.43
CYP19A1 P11511 1/20 0.43
TSHR P16473 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43
HTT P42858 1/20 0.43
HBB P68871 1/20 0.43
PMP22 Q01453 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4C Q9H3R0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1918404 0.83 ATAD2 (0.52) ATAD2DPYDMAPTGAAALDH1A1
SCHEMBL28113873 0.80
SCHEMBL8933555 0.79 GAA (0.48) ATAD2DPYDMAPTGAAALDH1A1
SCHEMBL7598527 0.79 HTR2A (0.45) ATAD2DPYDMAPTGAAALDH1A1
SCHEMBL17060272 0.76 ATAD2 (0.45) ATAD2DPYDMAPTGAAALDH1A1
SCHEMBL22017500 0.76 ATAD2 (0.45) ATAD2DPYDMAPTGAAALDH1A1
SCHEMBL7255538 0.76 ATAD2 (0.45) ATAD2DPYDMAPTGAAALDH1A1
SCHEMBL16893950 0.76 GAA (0.54) ATAD2DPYDMAPTGAAALDH1A1
SCHEMBL28699194 0.75 GAA (0.44) ATAD2DPYDMAPTGAAALDH1A1
SCHEMBL152546 0.75 DPYD (0.48) ATAD2DPYDMAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7264932-B2 Nuclease inhibitor cocktail APPLERA CORPORATION (US) 2007-09-04 US claimed
WO-2005083081-A1 IMPROVED NUCLEASE INHIBITOR COCKTAIL AMBION, INC. (US) 2005-09-09 WO claimed
US-20050014169-A1 Nuclease inhibitor cocktail AMBION, INC. 2005-01-20 US claimed
EP-3714263-B1 SYSTEM AND METHOD FOR THE ACOUSTIC LOADING OF AN ANALYTICAL INSTRUMENT USING A CONTINUOUS FLOW SAMPLING PROBE LABCYTE INC (US) 2025-07-23 EP disclosed
US-12154776-B2 System and method for the acoustic loading of an analytical instrument using a continuous flow sampling probe LABCYTE INC. (US) 2024-11-26 US disclosed
CN-109996881-B Efficient transfection of biological cells using acoustic perforation 拉伯塞特股份有限公司 2024-05-17 CN disclosed
EP-3512952-B1 HIGH-EFFICIENCY TRANSFECTION OF BIOLOGICAL CELLS USING SONOPORATION LABCYTE INC (US) 2024-05-15 EP disclosed
EP-3762491-B1 METHOD FOR EXTRACTING A TARGET MOIETY FROM A SAMPLE USING ACOUSTIC DROPLET EJECTION LABCYTE INC (US) 2023-09-20 EP disclosed
US-20230290627-A1 SYSTEM AND METHODFOR THE ACOUSTIC LOADINGOF ANANALYTICAL INSTRUMENT USING A CONTINUOUSFLOW SAMPLING PROBE LABCYTE, INC. (US) 2023-09-14 US disclosed
US-11637006-B2 System and method for the acoustic loading of an analytical instrument using a continuous flow sampling probe LABCYTE, INC. (US) 2023-04-25 US disclosed
US-20220155192-A1 SYSTEM AND METHOD FOR EXTRACTING A TARGET MOIETY FROM A SAMPLE USING ACOUSTIC DROPLET EJECTION LABCYTE, INC. 2022-05-19 US disclosed
WO-2004048611-A2 NUCLEIC ACID PROBES AND METHOD FOR DETECTING A TARGET NUCLEIC ACID SEQUENCE COMPRISE TWO OR MORE CIS- LOCATED NUCLEIC ACID REGIONS DYNAL BIOTECH LIMITED (GB) 2004-06-10 WO disclosed
EP-1409254-A1 ACOUSTIC EJECTION OF FLUIDS USING LARGE F-NUMBER FOCUSING ELEMENTS Picoliter, Inc. (US) 2004-04-21 EP disclosed
EP-1400601-A1 Method for detection of multiple nucleic acid sequence variations Bayer Healthcare LLC (US) 2004-03-24 EP disclosed
US-6693187-B1 ENHANCING NUCLEASE RESISTANCE LIEVRE CORNU LLC 2004-02-17 US disclosed
WO-2003022583-A1 ACOUSTIC EJECTION OF FLUIDS USING LARGE F-NUMBER FOCUSING ELEMENTS PICOLITER INC. (US) 2003-03-20 WO disclosed
US-20020086319-A1 Integrated device with surface-attached molecular moieties and related machine-readable information PICOLITER INC. 2002-07-04 US disclosed
WO-2002047075-A2 INTEGRATED DEVICE WITH SURFACE-ATTACHED MOLECULAR MOIETIES AND RELATED MACHINE-READABLE INFORMATION PICOLITER INC. (US) 2002-06-13 WO disclosed
US-20020042077-A1 Arrays of partially nonhybridizing oligonucleotides and preparation thereof using focused acoustic energy LABCYTE INC. 2002-04-11 US disclosed
WO-2002026756-A2 ARRAYS OF PARTIALLY NONHYBRIDIZING OLIGONUCLEOTIDES AND PREPARATION THEREOF USING FOCUSED ACOUSTIC ENERGY PICOLITER INC. (US) 2002-04-04 WO disclosed