Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1053233 | 0.84 | GAA (0.58) | GAANPC1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL28217739 | 0.84 | NPC1 (0.62) | GAANPC1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL25318113 | 0.82 | GAA (0.57) | GAANPC1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL4636570 | 0.79 | GAA (0.54) | GAANPC1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL11882343 | 0.79 | MGLL (0.72) | GAANPC1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL1587673 | 0.77 | GAA (0.59) | GAANPC1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL1060148 | 0.76 | GAA (0.57) | GAANPC1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL1578826 | 0.76 | ALDH1A1 (0.78) | GAANPC1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL3077817 | 0.76 | SMN1; SMN2 (0.72) | GAANPC1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL3900599 | 0.75 | GAA (0.76) | GAANPC1RAB9AMGLLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104024253-B | Heterocyclic amines as PI3K inhibitors | INCYTE HOLDINGS CORP. (US) | 2016-11-30 | — | — | CN | disclosed |