Acetamide

Acetamide

SCHEMBL28114072

CC(N)=O.O=[N+]([O-])c1cccc(N2CCCCC2)c1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.54
ALDH1A1 P00352 4/20 0.54
MAPT P10636 5/20 0.54
KDM4E B2RXH2 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
GAA P10253 2/20 0.51
LMNA P02545 2/20 0.51
SLC6A2 P23975 1/20 0.51
CHRNB4 P30926 1/20 0.51
CHRNA3 P32297 1/20 0.51
SLC6A3 Q01959 1/20 0.51
RAB9A P51151 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
HPGD P15428 2/20 0.49
ENPP2 Q13822 2/20 0.48
PKM P14618 1/20 0.48
MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2648360 0.90 MAPT (0.64) SMN1; SMN2ALDH1A1MAPTKDM4EMEN1
SCHEMBL20557972 0.90 MAPT (0.64) SMN1; SMN2ALDH1A1MAPTKDM4EMEN1
SCHEMBL533010 0.88 MAPT (0.66) SMN1; SMN2ALDH1A1MAPTKDM4EMEN1
SCHEMBL15272176 0.85 MAPT (0.66) SMN1; SMN2ALDH1A1MAPTKDM4EMEN1
SCHEMBL2655952 0.82 POLB (0.65) SMN1; SMN2ALDH1A1MAPTKDM4EMEN1
SCHEMBL6360154 0.79 LMNA (0.69) SMN1; SMN2ALDH1A1MAPTKDM4EMEN1
SCHEMBL2658444 0.78 POLB (0.52) SMN1; SMN2ALDH1A1MAPTKDM4EMEN1
Dinitrophenylene SCHEMBL27709667 0.78 TSHR (0.71) SMN1; SMN2ALDH1A1MAPTKDM4EMEN1
SCHEMBL1203455 0.78 SIRT6 (0.66) SMN1; SMN2ALDH1A1MAPTKDM4EMEN1
SCHEMBL30198400 0.78 SIRT6 (0.66) SMN1; SMN2ALDH1A1MAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106110358-A A kind of environment-friendly deodorant agent 苏州市易柯露环保科技有限公司 2016-11-16 CN disclosed