Chlorobenzene

Chlorobenzene

SCHEMBL28114087

CC(=NO)c1ccccc1.Clc1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
CA9 Q16790 3/20 0.44
LMNA P02545 3/20 0.44
HTT P42858 2/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
CASP3 P42574 1/20 0.43
GFER P55789 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
POLB P06746 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28280701 0.89 LMNA (0.52) CA9LMNAHTTMAPK1L3MBTL1
SCHEMBL2736631 0.89 LMNA (0.52) CA9LMNAHTTMAPK1L3MBTL1
SCHEMBL45278 0.89 LMNA (0.52) CA9LMNAHTTMAPK1L3MBTL1
SCHEMBL257242 0.89 LMNA (0.52) CA9LMNAHTTMAPK1L3MBTL1
SCHEMBL28059930 0.86 LMNA (0.50) CA9LMNAHTTMAPK1L3MBTL1
SCHEMBL27945945 0.86 LMNA (0.50) CA9LMNAHTTMAPK1L3MBTL1
SCHEMBL11235227 0.86 LMNA (0.50) CA9LMNAHTTMAPK1L3MBTL1
Water SCHEMBL4312372 0.86 LMNA (0.50) CA9LMNAHTTMAPK1L3MBTL1
SCHEMBL11266105 0.86 LMNA (0.50) CA9LMNAHTTMAPK1L3MBTL1
SCHEMBL265248 0.84 LMNA (0.57) TSHRCA9LMNAHTTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106146350-B A kind of new method of synthesizing amino formic acid oxime ester derivative 华南理工大学 2017-10-20 CN claimed
CN-106146350-A A kind of new method of synthesizing amino methylcarbamoyl oximino ester derivant 华南理工大学 2016-11-23 CN claimed
CN-110294758-A 2- replaces 5,6- dihydro-pyrazolo [5,1- α] isoquinolin, derivative and its synthetic method 湘潭大学 2019-10-01 CN disclosed
CN-109824660-A The method that rhodium catalysis arene oxidizing amination prepares the aromatic amine compounds of 2- pyridyl group substitution 陕西师范大学 2019-05-31 CN disclosed